Animal Genetics Dogs & Canines What dog is closest in DNA to a wolf? March 8, 2026 by pups | Leave a Comment The dog breed closest in DNA to a wolf is generally considered to be the Siberian Husky, followed closely by the Alaskan Malamute and the Shiba Inu. These breeds exhibit a higher degree of genetic similarity to ancient wolf populations than most other domestic dogs. Unraveling the Canine-Wolf Connection: Which Dog Breed Shares the Most […] Read more »