Animal Ethics What are the 5 R’s in animal research? January 30, 2026 by pups | Leave a Comment The "5 R’s" is not a commonly recognized framework in animal research. However, the principles of Replacement, Reduction, and Refinement, known as the "Three Rs," guide humane animal experimentation. These principles aim to minimize animal use and suffering while promoting ethical research practices. What are the core principles of the "Three Rs" in animal research? […] Read more »